OPTOGENETICS REFERENCES

Local negative feedback of Rac activity at the leading edge underlies a pilot pseudopod-like program for amoeboid guidance

Town JP, Weiner OD. PLoS Biology, 21:e3002307 (2023).

Optogenetic control of Yap reveals a dynamic communication code for stem cell fate and proliferation

Meyer, K., Lammers, N.C., Bugaj, L.J., Garcia, H.G., and Weiner, O.D. Nature Communication (2023).

Cell protrusions and contractions generate long-range membrane tension propagation

De Belly H, Yan S, Borja da Rocha H, Ichbiah S, Town JP, Zager PJ, Estrada DC, Meyer K, Turlier H, Bustamante C, Weiner OD. Cell, 14: 3049-3061. (2023).

Light-based tuning of ligand half-life supports kinetic proofreading model of T cell activation.

Tischer D, Weiner OD. eLife, 8: 42498 (2019).

A module for Rac temporal signal integration revealed with optogenetics.

Graziano BR, Gong D, Anderson KE, Pipathsouk A, Goldberg AR, Weiner OD. J. Cell Biol., 216: 2515-2531 (2017).

TAEL: a zebrafish-optimized gene expression system with fine spatial and temporal control

Reade A, Motta-Mena LB, Stainier DY, Weiner OD#, Woo S#. Development, 144: 345-355 (2017). (#corresponding author)

Reversible optogenetic control of subcellular protein localization in a live vertebrate embryo.

Buckley CE, Moore RE, Reade A, Goldberg A, Weiner OD#, Clarke JDW#. Developmental Cell, 36: 117-26 (2016). (#corresponding author)

Probing yeast polarity with acute, reversible, optogenetic inhibition of protein function.

Jost AP, Weiner OD. ACS Synthetic Biology, 4: 1077-85 (2015).

Illuminating cell signaling with optogenetic tools.

Tischer D, Weiner OD. Nature Reviews Molecular and Cellular Biology, 15: 551-8 (2014).

Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.

Toettcher JE, Weiner OD#, Lim WA#. Cell, 155: 1422-1434 (2013). (#corresponding author)

Editor’s Choice, Science Signaling
Recommended by Faculty of 1000

Light-based feedback for controlling intracellular signaling dynamics.

Toettcher JE, Gong D, Lim WA, Weiner OD. Nature Methods, 8: 837-9 (2011).